Our science
Where genomics and clinical medicine meet
OpenDNA combines cutting-edge polygenic science with clinical data integration to deliver risk insights that are more accurate, more personalized, and more actionable than any single source of data alone.
01
Polygenic Risk Scores (PRS)
Unlike single-gene tests, our polygenic models analyze over one million genetic variants or SNPs (Single Nucleotide Polymorphisms) simultaneously. This captures the cumulative effect of your entire genome on condition risk — providing far greater predictive power than traditional genetic screening.
02
Clinical data integration
Genetic signals become far more powerful when combined with clinical measurements. Our models integrate your genetic profile with clinical and lifestyle factors — delivering a complete, personalized risk picture based on both your genetic and clinical profile.
03
Validated predictive models
Our models are built on peer-reviewed research and validated against large population cohorts. Each risk score is calibrated to reflect your risk relative to the general population, giving you a meaningful benchmark for proactive action.
Explore the research behind our models
04
Physician-reviewed insights
Every report is reviewed and signed by a licensed physician. Our clinical team ensures that insights are medically accurate, contextually relevant, and actionable — not just a data printout.
"Genetics alone isn't enough. The future of preventive medicine combines your DNA with who you are clinically — and what you can change."
OpenDNA Science Team